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Hyperplasia

Hypergenesis

Hyperplasia is increased cell production in a normal tissue or organ. Hyperplasia may be a sign of abnormal or precancerous changes. This is called pathologic hyperplasia.

It can also be due to the increased growth of normal cells. This is called physiologic hyperplasia. An example of physiologic hyperplasia is an increase in the number of prostate cells most often seen in older men (benign prostatic hyperplasia).

References

Aster JC, Abbas AK, Kumar V, Debnath J, Das A. Cell injury, cell death, and adaptations. In: Kumar V, Abbas AK, Aster JC, eds. Robbins, Cotran & Kumar Pathologic Basis of Disease. 11th ed. Philadelphia, PA: Elsevier; 2026:chap 2.

    • Hyperplasia

      Hyperplasia - illustration

      Hyperplasia is the increased cell production of normal tissue in the body which causes the organ to increase in size.

      Hyperplasia

      illustration

      • Hyperplasia

        Hyperplasia - illustration

        Hyperplasia is the increased cell production of normal tissue in the body which causes the organ to increase in size.

        Hyperplasia

        illustration

      A Closer Look

       

      Tests for Hyperplasia

       

      Review Date: 7/3/2025

      Reviewed By: Robert Hurd, MD, Professor of Endocrinology and Health Care Ethics, Xavier University, Cincinnati, OH. Review provided by VeriMed Healthcare Network. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.

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