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Absence of sweating

Decreased sweating; Anhidrosis

An abnormal lack of sweat in response to heat may be harmful because sweating allows heat to be released from the body. The medical term for absent sweating is anhidrosis.

Considerations

Anhidrosis sometimes goes unrecognized until a substantial amount of heat or exertion fails to cause sweating.

Overall lack of sweating can be life threatening because the body will overheat. If the lack of sweating happens in a small area only, it is usually not as dangerous.

Causes

Cause of anhidrosis may include:

  • Burns
  • Brain tumor
  • Certain genetic syndromes
  • Certain nerve problems (neuropathies)
  • Congenital disorders including ectodermal dysplasia
  • Dehydration
  • Nervous system disorders such as Guillain-Barré syndrome
  • Skin diseases or scarring of the skin that block sweat glands
  • Trauma to sweat glands
  • Use of certain medicines

Home Care

If there is a danger of overheating, take the following measures:

  • Take a cool shower or sit in a bathtub with cool water
  • Drink plenty of fluids
  • Stay in a cool environment
  • Move slowly
  • Do not do heavy exercise

When to Contact a Medical Professional

Contact your health care provider if you have a general lack of sweating or an abnormal lack of sweating when exposed to heat or strenuous exercise.

What to Expect at Your Office Visit

Your provider will perform a physical exam. In emergencies, your health care team will perform rapid cooling measures and give you fluids to stabilize you.

You may be asked about your symptoms and medical history.

You may be asked to wrap yourself in an electric blanket or sit in a sweatbox while your health care team watches your body's reaction. Other tests to cause and measure sweating may also be done.

A skin biopsy may be done. Genetic testing may be done if appropriate.

Treatment depends on the cause of your lack of sweating. You may be given medicine to cause sweating.

References

James WD. Diseases of the skin appendages. In: James WD, ed. Andrews' Diseases of the Skin: Clinical Dermatology. 14th ed. Philadelphia, PA: Elsevier; 2026:chap 28.

Miller JL. Diseases of the eccrine and apocrine sweat glands. In: Bolognia JL, Schaffer JV, Cerroni L, eds. Dermatology. 5th ed. Philadelphia, PA: Elsevier; 2025:chap 39.

          Review Date: 6/3/2025

          Reviewed By: Ramin Fathi, MD, FAAD, Director, Phoenix Surgical Dermatology Group, Phoenix, AZ. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.

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