Epicanthal folds
Plica palpebronasalisAn epicanthal fold is skin of the upper eyelid that covers the inner corner of the eye. The fold runs from the nose to the inner side of the eyebrow.
Causes
Epicanthal folds may be normal for people of Asian descent and some non-Asian infants. Epicanthal folds also may be seen in young children of any race before the bridge of the nose begins to rise.
However, they may also be due to certain medical conditions, including:
- Down syndrome
Down syndrome
Down syndrome is a genetic condition in which a person has 47 chromosomes instead of the usual 46.
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Home Care
In most cases, no home care is needed.
When to Contact a Medical Professional
This trait is most often found before or during the first well-baby exam. Contact your health care provider if you notice epicanthal folds on your child's eyes and the reason for their presence is unknown.
What to Expect at Your Office Visit
Your provider will examine the child and ask questions about the medical history and symptoms. Questions may include:
- Do any family members have Down syndrome or other genetic disorder?
- Is there a family history of intellectual disability or birth defects?
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A child who is not Asian and is born with epicanthal folds may be examined for additional signs of Down syndrome or other genetic disorders.
References
Madan-Khetarpal S, Arnold G, Ortiz D. Genetic disorders and dysmorphic conditions. In: Zitelli BJ, McIntire SC, Nowalk AJ, Garrison J, eds. Zitelli and Davis' Atlas of Pediatric Physical Diagnosis. 8th ed. Philadelphia, PA: Elsevier; 2023:chap 1.
Olitsky SE, Marsh JD. Abnormalities of the lids. In: Kliegman RM, St. Geme JW, Blum NJ, et al, eds. Nelson Textbook of Pediatrics. 22nd ed. Philadelphia, PA: Elsevier; 2025:chap 664.
Orge FH, Salem ZM. Examination and common problems in the neonatal eye. In: Martin RJ, Fanaroff AA, eds. Fanaroff and Martin's Neonatal-Perinatal Medicine. 12th ed. Philadelphia, PA: Elsevier; 2025:chap 99.
The face - illustration
The physical landmarks of the human face are very similar from one face to another.
The face
illustration
Epicanthal fold - illustration
An epicanthal fold is a skin fold of the upper eyelid covering the inner corner of the eye. It is often seen as a normal finding in very young children and is also common in certain ancestry groups. An epicanthal fold can be an important diagnostic finding in conditions such as Down syndrome.
Epicanthal fold
illustration
Epicanthal folds - illustration
The epicanthal fold is the skin fold of the upper eyelid covering the inner corner of the eye, most usually seen in certain ancestry groups.
Epicanthal folds
illustration
The face - illustration
The physical landmarks of the human face are very similar from one face to another.
The face
illustration
Epicanthal fold - illustration
An epicanthal fold is a skin fold of the upper eyelid covering the inner corner of the eye. It is often seen as a normal finding in very young children and is also common in certain ancestry groups. An epicanthal fold can be an important diagnostic finding in conditions such as Down syndrome.
Epicanthal fold
illustration
Epicanthal folds - illustration
The epicanthal fold is the skin fold of the upper eyelid covering the inner corner of the eye, most usually seen in certain ancestry groups.
Epicanthal folds
illustration
Review Date: 1/17/2025
Reviewed By: Charles I. Schwartz, MD, FAAP, Clinical Assistant Professor of Pediatrics, Perelman School of Medicine at the University of Pennsylvania, General Pediatrician at PennCare for Kids, Phoenixville, PA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.
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