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    Translocation

    Translocation means a change in location. It often refers to genetics, when part of a chromosome is transferred to another chromosome. Chromosomes are structures that carry genes, our units of heredity. When a translocation occurs, it can cause flaws in chromosomes.

    In another type of translocation, two chromosomes trade pieces with each other.

    Genetic translocations can cause serious disorders, including a type of leukemia.

    Open References

    References

    Kumar V, Abbas AK, Aster JC. Neoplasia. In: Kumar V, Abbas AK, Aster JC, eds. Robbins & Cotran Pathologic Basis of Disease. 10th ed. Philadelphia, PA: Elsevier; 2021:chap 7.

      • Chromosomes and DNA

        Chromosomes and DNA - illustration

        Humans typically have 23 pairs of chromosomes, or 46 chromosomes in total. Chromosomes are made up of long strands of DNA, which contain all the body's genes.

        Chromosomes and DNA

        illustration

        • Chromosomes and DNA

          Chromosomes and DNA - illustration

          Humans typically have 23 pairs of chromosomes, or 46 chromosomes in total. Chromosomes are made up of long strands of DNA, which contain all the body's genes.

          Chromosomes and DNA

          illustration

        Review Date: 11/1/2023

        Reviewed By: Linda J. Vorvick, MD, Clinical Professor, Department of Family Medicine, UW Medicine, School of Medicine, University of Washington, Seattle, WA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.

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