Pulmonary nocardiosis
Nocardiosis - pulmonary; Mycetoma; NocardiaPulmonary nocardiosis is an infection of the lung with Nocardia bacteria.
Causes
Nocardia infection develops when you breathe in (inhale) the bacteria. The infection causes pneumonia-like symptoms. The infection can spread to any part of the body.
Pneumonia
Pneumonia is a breathing (respiratory) condition in which there is an infection of the lung. This article covers community-acquired pneumonia (CAP). ...
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People with a weak immune system are at a high risk for nocardia infection. This includes people who have:
- Been taking steroids or other medicines that weaken the immune system for a long time
- Cushing disease
Cushing disease
Cushing disease is a condition in which the pituitary gland releases too much adrenocorticotropic hormone (ACTH). The pituitary gland is an organ of...
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- HIV/AIDS
HIV/AIDS
Human immunodeficiency virus (HIV) is the virus that causes acquired immunodeficiency syndrome (AIDS). When a person becomes infected with HIV, the ...
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Cancer
Cancer is the uncontrolled growth of abnormal cells in the body. Cancerous cells are also called malignant cells.
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Other people at risk include those with long-term (chronic) lung problems related to smoking, emphysema, or tuberculosis.
Emphysema
Chronic obstructive pulmonary disease (COPD) is a common lung disease. Having COPD makes it hard to breathe. There are two main forms of COPD:Chroni...
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Tuberculosis
Pulmonary tuberculosis (TB) is a contagious bacterial infection that involves the lungs. It may spread to other organs.
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Symptoms
Pulmonary nocardiosis mainly affects the lungs. But, nocardiosis can also spread to other organs in the body. Common symptoms may include:
ENTIRE BODY
- Fever (comes and goes)
Fever
Fever is the temporary increase in the body's temperature in response to a disease or illness. A child has a fever when the temperature is at or abov...
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Malaise
Malaise is a general feeling of discomfort, illness, or lack of well-being.
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GASTROINTESTINAL SYSTEM
- Nausea
- Liver and spleen swelling (hepatosplenomegaly)
Hepatosplenomegaly
Enlarged liver refers to swelling of the liver beyond its normal size. Hepatomegaly is another word to describe this problem. If both the liver and ...
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- Unintentional weight loss
Unintentional weight loss
Unexplained weight loss is a decrease in body weight, when you did not try to lose the weight on your own. Many people gain and lose weight. Uninten...
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LUNGS AND AIRWAYS
- Breathing difficulty
Breathing difficulty
Breathing difficulty may involve:Difficult breathing Uncomfortable breathingFeeling like you are not getting enough air
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- Coughing up blood or mucus
Coughing up blood
Coughing up blood is the spitting up of blood or bloody mucus from the lungs and throat (respiratory tract). Hemoptysis is the medical term for cough...
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- Shortness of breath
MUSCLES AND JOINTS
NERVOUS SYSTEM
- Change in mental state
- Confusion
Confusion
Confusion is the inability to think as clearly or quickly as you normally do. You may feel disoriented and have difficulty paying attention, remembe...
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Dizziness
Dizziness is a term that is often used to describe 2 different symptoms: lightheadedness and vertigo. Lightheadedness is a feeling that you might fai...
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Headache
A headache is pain or discomfort in the head, scalp, or neck. Serious causes of headaches are rare. Most people with headaches can feel much better...
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Seizures
A seizure is the physical changes in behavior that occurs during an episode of specific types of abnormal electrical activity in the brain. The term ...
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SKIN
- Skin rashes or lumps
Rashes
Rashes involve changes in the color, feeling or texture of your skin.
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Abscesses
An abscess is a collection of pus in any part of the body. In most cases, the area around an abscess is swollen and inflamed.
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Swollen lymph nodes
Lymph nodes are present throughout your body. They are an important part of your immune system. Lymph nodes help your body recognize and fight germ...
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Exams and Tests
Your health care provider will examine you and listen to your lungs using a stethoscope. You may have abnormal lung sounds, called crackles. Tests that may be done include:
- Bronchoalveolar lavage -- fluid is sent for stain and culture, which is taken by bronchoscopy
Bronchoscopy
Bronchoscopy is a test to view the airways and diagnose lung disease. It may also be used during the treatment of some lung conditions.
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Chest x-ray
A chest x-ray is an x-ray of the chest, lungs, heart, large arteries, ribs, and diaphragm.
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Chest CT
A chest CT (computed tomography) scan is an imaging method that uses x-rays to create cross-sectional pictures of the chest and upper abdomen....
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MRI scan of the chest
A chest MRI (magnetic resonance imaging) scan is an imaging test that uses powerful magnetic fields and radio waves to create pictures of the chest (...
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Pleural fluid culture
Pleural fluid culture is a test that examines a sample of fluid that has been collected in the pleural space to see if you have an infection to help ...
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Culture
Routine sputum culture is a laboratory test that looks for germs that cause infection. Sputum is the material that comes up from air passages when y...
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Treatment
The goal of treatment is to cure the infection. Antibiotics are used, but it may take a while to get better. Your provider will tell you how long you need to take the medicines. This may be for up to a year.
Surgery may be needed to remove or drain infected areas.
Your provider may tell you to stop taking any medicines that weaken your immune system. Never stop taking any medicine before talking to your provider first.
Outlook (Prognosis)
The outcome is often good when the condition is diagnosed and treated quickly.
The outcome is poor when:
- The infection spreads outside the lung.
- Treatment is delayed.
- The person has a serious disease that leads to or requires long-term suppression of the immune system.
Possible Complications
Complications of pulmonary nocardiosis may include:
- Brain abscesses
Brain abscesses
A brain abscess is a collection of pus, immune cells, and other material in the brain, caused by a bacterial or fungal infection.
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- Kidney infections
When to Contact a Medical Professional
Contact your provider if you have symptoms of this disorder. Early diagnosis and treatment may improve the chance of a good outcome.
Prevention
Be careful when using corticosteroids. Use these medicines sparingly, in the lowest effective doses and for the shortest period of time possible.
Some people with a weak immune system may need to take antibiotics for long period of time or indefinitely to prevent the infection from returning.
References
Dockrell DH, Ho A, Gordon SB. Community-acquired pneumonia. In: Broaddus VC, Ernst JD, King Jr TE, et al, eds. Murray and Nadel's Textbook of Respiratory Medicine. 7th ed. Philadelphia, PA: Elsevier; 2022:chap 46.
Southwick FS. Nocardiosis. In: Goldman L, Cooney KA, eds. Goldman-Cecil Medicine. 27th ed. Philadelphia, PA: Elsevier; 2024:chap 306.
Respiratory system - illustration
Air is breathed in through the nasal passageways, travels through the trachea and bronchi to the lungs.
Respiratory system
illustration
Review Date: 8/19/2024
Reviewed By: Allen J. Blaivas, DO, Division of Pulmonary, Critical Care, and Sleep Medicine, VA New Jersey Health Care System, Clinical Assistant Professor, Rutgers New Jersey Medical School, East Orange, NJ. Review provided by VeriMed Healthcare Network. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.